Public Health

Scientists in Scotland’s Dundee University discover new anti-malaria drug


Scientists at Dundee University Scotland have discovered a new anti-malarial compound that could treat patients with a single $1 dose.
The compound identified as DDD107498, was developed by Dundee University’s Drug Discovery Unit and the Medicines for Malaria Venture.
Scientists said the “exciting” new drug could work well against parasites resistant to current treatments.
DDD107498 was tested in human blood and in mice models also. It showed  a capacity to kill the parasite in mice.
When administered to human cells at high doses, the drug appeared  non-toxic.
Current drugs available in the market only treat malaria at the blood cell stage, where symptoms come out. However, they do not target parasites that are already in the transmission phase meaning the parasites could be picked up again by mosquitoes and the spread of the disease continues.
Interestingly, the new compound targets all various phases of the life cycle of malarial parasites in the body.


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